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Volume 11, Number 9:4006-4641;2021
American Journal of Cancer Research


Anca-Narcisa Neagu, Danielle Whitham, Emma Buonanno, Avalon Jenkins, Teodora Alexa-Stratulat, Bogdan Ionel Tamba, Costel C Darie: Proteomics and its applications in breast cancer. Am J Cancer Res 2021;11(9):4006-4049. (Abstract ajcr0129953, Full text, PDF).

Paulius Gibieža, Vilma Petrikaitė: The regulation of actin dynamics during cell division and malignancy. Am J Cancer Res 2021;11(9):4050-4069. (Abstract ajcr0136231, Full text, PDF).

Valentina K Todorova, Jeanne Y Wei, Issam Makhoul: Subclinical doxorubicin-induced cardiotoxicity update: role of neutrophils and endothelium. Am J Cancer Res 2021;11(9):4070-4091. (Abstract ajcr0135493, Full text, PDF).

Sosuke Sahara, Alexandra E Herzog, Jacques E Nör: Systemic therapies for salivary gland adenoid cystic carcinoma. Am J Cancer Res 2021;11(9):4092-4110. (Abstract ajcr0136507, Full text, PDF).

Silvia Lemma, Anna M Perrone, Pierandrea De Iaco, Giuseppe Gasparre, Ivana Kurelac: Current methodologies to detect circulating tumor cells: a focus on ovarian cancer. Am J Cancer Res 2021;11(9):4111-4126. (Abstract ajcr0136241, Full text, PDF).

Adriana Ramírez-Cosmes, Edilburga Reyes-Jiménez, Cecilia Zertuche-Martínez, Carlos A Hernández-Hernández, Rebeca García-Román, Roberto I Romero-Díaz, Adán E Manuel-Martínez, Jesús Elizarrarás-Rivas, Verónica R Vásquez-Garzón: The implications of ABCC3 in cancer drug resistance: can we use it as a therapeutic target? Am J Cancer Res 2021;11(9):4127-4140. (Abstract ajcr0134470, Full text, PDF).

Xuewei Bai, Yanmei Zhou, Qiushi Lin, Chiung-Kuei Huang, Songhua Zhang, Rolf I Carlson, Hossein Ghanbari, Bei Sun, Jack R Wands, Xiaoqun Dong: Bio-nanoparticle based therapeutic vaccine induces immunogenic response against triple negative breast cancer. Am J Cancer Res 2021;11(9):4141-4174. (Abstract ajcr0135005, Full text, PDF).

Ming-Chun Lai, Qian-Qian Zhu, Jun Xu, Wen-Jin Zhang: Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development. Am J Cancer Res 2021;11(9):4175-4198. (Abstract ajcr0135504, Full text, PDF).

Atikul Islam, Pei-Fang Hsieh, Pei-Fen Liu, Jou-Chun Chou, Jiunn-Wang Liao, Ming-Kun Hsieh, Pin Ju Chueh: Capsaicin exerts therapeutic effects by targeting tNOX-SIRT1 axis and augmenting ROS-dependent autophagy in melanoma cancer cells. Am J Cancer Res 2021;11(9):4199-4219. (Abstract ajcr0134819, Full text, PDF).

Ying-Chen Chen, Chu-Yen Chien, Chia-Chen Hsu, Chien-Hsing Lee, Yu-Ting Chou, Shine-Gwo Shiah, Shyun-Yeu Liu, Ching-Yu Yen, Alexander Cheng-Ting Hsieh, Martin Wabitsch, Yi-Shing Shieh: Obesity-associated leptin promotes chemoresistance in colorectal cancer through YAP-dependent AXL upregulation. Am J Cancer Res 2021;11(9):4220-4240. (Abstract ajcr0135456, Full text, PDF).

Yan Zhuang, Yue Ma, Sunshun Yan, Bing Zhao, Shuling Wu, Qianwen Zhang, Xiaoying Huang, Haiyang Zhao, Chengguang Zhao, Zhiguo Liu, Lehe Yang: Cyy260, a novel small molecule inhibitor, suppresses non-small cell lung cancer cell growth via JAK2/STAT3 pathway. Am J Cancer Res 2021;11(9):4241-4258. (Abstract ajcr0133470, Full text, PDF).

Haiping Jiang, Ning Li, Huan Wang, Zhenguang Chen, Yulong Zheng, Jiong Qian, Chenyu Mao, Xin Xu, Cheng Xiao, Xiaochen Zhang, Hui Zhou, Shuyan Wang, Weisheng Chen, Xia Yin, Jiya Sun, Bo Peng, Lisong Teng, Nong Xu: Assessment of TMB, PD-L1, and lymphocyte to monocyte ratio as predictive potential in a phase Ib study of sintilimab in patients with advanced solid tumors. Am J Cancer Res 2021;11(9):4259-4276. (Abstract ajcr0136422, Full text, PDF).

Yi-Ling Chen, Chih-Yang Wang, Jung-Hua Fang, Hui-Ping Hsu: Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness. Am J Cancer Res 2021;11(9):4277-4293. (Abstract ajcr0133231, Full text, PDF).

Eriko Katsuta, Michelle Huyser, Li Yan, Kazuaki Takabe: A prognostic score based on long-term survivor unique transcriptomic signatures predicts patient survival in pancreatic ductal adenocarcinoma. Am J Cancer Res 2021;11(9):4294-4307. (Abstract ajcr0135698, Full text, PDF).

Bei Zhao, Xiaodan Hui, Jie Wang, Hairong Zeng, Yu Yan, Qing Hu, Guangbo Ge, Tao Lei: Matrine suppresses lung cancer metastasis via targeting M2-like tumour-associated-macrophages polarization. Am J Cancer Res 2021;11(9):4308-4328. (Abstract ajcr0133642, Full text, PDF).

Wenjuan He, Mingyang Qin, Yue Cai, Xiujuan Gao, Sisi Cao, Zhuo Wang, Hui Chen, Rong Xu: Downregulation of HOXC6 by miR-27a ameliorates gefitinib resistance in non-small cell lung cancer. Am J Cancer Res 2021;11(9):4329-4346. (Abstract ajcr0113852, Full text, PDF).

Xiaojie Tan, Shaoling Zheng, Wenbin Liu, Yan Liu, Zhengchun Kang, Zishuai Li, Peng Li, Jiahui Song, Jianguo Hou, Bo Yang, Xue Han, Fubo Wang, Chunxia Jing, Guangwen Cao: Effect of APOBEC3A functional polymorphism on renal cell carcinoma is influenced by tumor necrosis factor-α and transcriptional repressor ETS1. Am J Cancer Res 2021;11(9):4347-4363. (Abstract ajcr0127932, Full text, PDF).

Motomichi Fujita, Manabu Sasada, Mayu Eguchi, Takuya Iyoda, Shin Okuyama, Takuro Osawa, Kenta Tsuzuranuki, Mamoru Sakamoto, Yu Hagihara, Masaki Matsumura, Satoshi Osada, Hiroaki Kodama, Yoshikazu Higami, Fumio Fukai: Induction of cellular senescence in fibroblasts through β1-integrin activation by tenascin-C-derived peptide and its protumor effect. Am J Cancer Res 2021;11(9):4364-4379. (Abstract ajcr0136961, Full text, PDF).

Weijun Liu, Zhiqing Zhou, Yu Li, Jiali Xu, Yang Shen, Suisui Luo, Yujie Zhou, Xing Wu, Huijie Zhao, David G Beer, Yanli He, Guoan Chen: CSE1L silencing impairs tumor progression via MET/STAT3/PD-L1 signaling in lung cancer. Am J Cancer Res 2021;11(9):4380-4393. (Abstract ajcr0133305, Full text, PDF).

Vikas Satyananda, Masanori Oshi, Yoshihisa Tokumaru, Aparna Maiti, Nitai Hait, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe: Sphingosine 1-phosphate (S1P) produced by sphingosine kinase 1 (SphK1) and exported via ABCC1 is related to hepatocellular carcinoma (HCC) progression. Am J Cancer Res 2021;11(9):4394-4407. (Abstract ajcr0137468, Full text, PDF).

Konstantinos Chouliaras, Masanori Oshi, Mariko Asaoka, Yoshihisa Tokumaru, Thaer Khoury, Itaru Endo, Takashi Ishikawa, Kazuaki Takabe: Increased intratumor heterogeneity, angiogenesis and epithelial to mesenchymal transition pathways in metaplastic breast cancer. Am J Cancer Res 2021;11(9):4408-4420. (Abstract ajcr0135814, Full text, PDF).

Masanori Oshi, Shipra Gandhi, Michelle R Huyser, Yoshihisa Tokumaru, Li Yan, Akimitsu Yamada, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe: MELK expression in breast cancer is associated with infiltration of immune cell and pathological compete response (pCR) after neoadjuvant chemotherapy. Am J Cancer Res 2021;11(9):4421-4437. (Abstract ajcr0135977, Full text, PDF).

Alfredo Minguela, María A Vasco-Mogorrón, José A Campillo, Valentin Cabañas, María J Remigia, Mercedes Berenguer, María C García-Garay, Miguel Blanquer, Catalina Cava, José Antonio Galian, Lourdes Gimeno, María F Soto-Ramírez, María D Martínez-Hernández, Javier de la Rubia, Ana I Teruel, Manuel Muro, Adela Periago: Predictive value of 1q21 gain in multiple myeloma is strongly dependent on concurrent cytogenetic abnormalities and first-line treatment. Am J Cancer Res 2021;11(9):4438-4454. (Abstract ajcr0136158, Full text, PDF).

You-Zhe Lin, Chuan-Chun Lee, Der-Yang Cho, Yuan-Liang Wang, Chia-Yun Chen, Ching-Yu Weng, Shao-Chih Chiu, Mien-Chie Hung, Shao-Chun Wang:
Suppression of breast cancer cells resistant to a pure anti-estrogen with CAR-transduced natural killer cells. Am J Cancer Res 2021;11(9):4455-4469. (Abstract ajcr0121778, Full text, PDF).

Karoline V Gleixner, Yüksel Filik, Daniela Berger, Christina Schewzik, Gabriele Stefanzl, Irina Sadovnik, Lina Degenfeld-Schonburg, Gregor Eisenwort, Mathias Schneeweiss-Gleixner, Konstantin Byrgazov, Wolfgang R Sperr, Jiří Mayer, Thomas Lion, Peter Valent: Asciminib and ponatinib exert synergistic anti-neoplastic effects on CML cells expressing BCR-ABL1T315I-compound mutations. Am J Cancer Res 2021;11(9):4470-4484. (Abstract ajcr0133715, Full text, PDF).

Han Li, Xian-Liang Li, Shuang Cao, Ya-Nan Jia, Ruo-Lin Wang, Wen-Li Xu, Ren Lang, Qiang He, Ji-Qiao Zhu: Decreased granzyme B+CD19+B cells are associated with tumor progression following liver transplantation. Am J Cancer Res 2021;11(9):4485-4499. (Abstract ajcr0134545, Full text, PDF).

Massimiliano Dall’Ora, Giulia Rovesti, Luca Reggiani Bonetti, Giulia Casari, Federico Banchelli, Luca Fabbiani, Elena Veronesi, Tiziana Petrachi, Paolo Magistri, Fabrizio Di Benedetto, Andrea Spallanzani, Chiara Chiavelli, Maria Carlotta Spano, Antonino Maiorana, Massimo Dominici, Giulia Grisendi: TRAIL receptors are expressed in both malignant and stromal cells in pancreatic ductal adenocarcinoma. Am J Cancer Res 2021;11(9):4500-4514. (Abstract ajcr0135860, Full text, PDF).

Jing Wang, Yingbo Li, Chun-Mei Wan, Zong-Jie Gan, Lin-Ling Gan, Bai-Cheng He, Yu Yu, Xue-Lian Hu: PTEN inhibition leads to the development of resistance to novel isoquinoline derivative TNBG-5602 in human liver cancer cells. Am J Cancer Res 2021;11(9):4515-4527. (Abstract ajcr0135312, Full text, PDF).

Jingkai Sun, Wenfeng Lin, Chaoming Li, Hideo Ueki, Ruizhi Xue, Takuya Sadahira, Hao Hu, Koichiro Wada, Na Li, Chunxiao Liu, Motoo Araki, Abai Xu, Peng Huang: Repurposing of posaconazole as a hedgehog/SMO signaling inhibitor for embryonal rhabdomyosarcoma therapy. Am J Cancer Res 2021;11(9):4528-4540. (Abstract ajcr0136256, Full text, PDF).

Kyung-Ran Park, Hyun Hee Leem, Joonyeop Lee, Il Keun Kwon, Jin Tae Hong, Hyung-Mun Yun: Anti-cancer effects of Hederoside C, a pentacyclic triterpene saponin, through the intrinsic apoptosis and STAT3 signaling pathways in osteosarcoma. Am J Cancer Res 2021;11(9):4541-4550. (Abstract ajcr0137052, Full text, PDF).

Anwen Xiong, Ning Ma, Guo Wei, Chunhua Li, Kainan Li, Bin Wang: Genomic alterations in tumor tissue and ctDNA from Chinese pancreatic cancer patients. Am J Cancer Res 2021;11(9):4551-4567. (Abstract ajcr0134475, Full text, PDF).

Noura Khaled, Nicolas Sonnier, Ioana Molnar, Flora Ponelle-Chachuat, Myriam Kossai, Nina Radosevic-Robin, Maud Privat, Yannick Bidet: RNA sequencing reveals the differential expression profiles of RNA in metastatic triple negative breast cancer and identifies SHISA3 as an efficient tumor suppressor gene. Am J Cancer Res 2021;11(9):4568-4581. (Abstract ajcr0133584, Full text, PDF).

Won Seok Lee, Seung-Jun Seo, Hye Kyung Chung, Jang Woo Park, Jong-Ki Kim, Eun Ho Kim: Tumor-treating fields as a proton beam-sensitizer for glioblastoma therapy. Am J Cancer Res 2021;11(9):4582-4594. (Abstract ajcr0137079, Full text, PDF).

Yuanyuan Zhang, Lin Li, Ziyi Wang, Yi Huang, Suiyu Luo, Yongmei Peng, Ning Li, Yang He, Chunmei Li, Keqiang Zhang, Hongying Yang, Qi Zhou, Lingying Wu: Preferred method of therapy for patients with early-stage high-grade neuroendocrine carcinoma of the cervix. Am J Cancer Res 2021;11(9):4595-4606. (Abstract ajcr0134117, Full text, PDF).

Robyn Borsuk, Lanlan Zhou, Wen-I Chang, Yiqun Zhang, Aditi Sharma, Varun V Prabhu, Nikos Tapinos, Rishi R Lulla, Wafik S El-Deiry: Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosis. Am J Cancer Res 2021;11(9):4607-4623. (Abstract ajcr0136157, Full text, PDF).

Goni Katz-Greenberg, Sushil Ghimire, Tinging Zhan, Kashka Mallari, Diana Whitaker-Menezes, Jerald Gong, Guldeep Uppal, Ubaldo Martinez-Outschoorn, Maria P Martinez Cantarin: Post-transplant lymphoproliferative disorders (PTLD)-from clinical to metabolic profiles-a single center experience and review of literature. Am J Cancer Res 2021;11(9):4624-4637. (Abstract ajcr0135881, Full text, PDF).

Chan-Chuan Liu, Cheng-Lin Wu, I-Chun Yeh, Sheng-Nan Wu, Chun-I Sze, Po-Wu Gean: Cilostazol eliminates radiation-resistant glioblastoma by re-evoking big conductance calcium-activated potassium channel activity: Am J Cancer Res. 2021; 11(4): 1148-1169. Am J Cancer Res 2021;11(9):4638-4640. (Abstract ajcr0136123, Full text, PDF).

Retraction: microRNA-532 suppresses the PI3K/Akt signaling pathway to inhibit colorectal cancer progression by directly targeting IGF-1R. Am J Cancer Res 2021;11(9):4641. (Abstract ajcr0137633, Full text, PDF).
American Journal of Cancer Research
ISSN: 2156-6976